Falcarinol
Product Specifications
UNSPSC Description
Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. Falcarinol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Apoptosis; HSP
Type
Natural Products
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/falcarinol.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
C=C[C@@H](O)C#CC#CC/C=C\CCCCCCC
Molecular Weight
244.37
References & Citations
[1]Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1455/Falcarinol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1455/Falcarinol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
21852-80-2
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