Elotuzumab
Elotuzumab (HuLuc 63) is an IgG1 monoclonal antibody targeting the SLAMF7 receptor. Elotuzumab exerts antitumor activity by activating natural killer cells and inducing antibody-dependent cell-mediated cytotoxicity. Elotuzumab can be combined with Lenalidomide , Dexamethasone (HY-14648), etc., for the research of tumors such as multiple myeloma[1][2].
Product Specifications
CAS Number
915296-00-3
Product Name Alternative
HuLuc 63; PDL 063; BMS 901608
UNSPSC
12352203
Target
Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/elotuzumab.html
Purity
99.9
Solubility
H2O
Smiles
[Elotuzumab]
Molecular Weight
(145.44 kDa)
References & Citations
[1]Magen H, et al. Elotuzumab: the first approved monoclonal antibody for multiple myeloma treatment. Ther Adv Hematol. 2016;7 (4) :187-195.|[2]Bezman NA, et al. PD-1 blockade enhances elotuzumab efficacy in mouse tumor models. Blood Adv. 2017 May 8;1 (12) :753-765.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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