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Elotuzumab

Elotuzumab (HuLuc 63) is an IgG1 monoclonal antibody targeting the SLAMF7 receptor. Elotuzumab exerts antitumor activity by activating natural killer cells and inducing antibody-dependent cell-mediated cytotoxicity. Elotuzumab can be combined with Lenalidomide , Dexamethasone (HY-14648), etc., for the research of tumors such as multiple myeloma[1][2].

Product Specifications

CAS Number

915296-00-3

Product Name Alternative

HuLuc 63; PDL 063; BMS 901608

UNSPSC

12352203

Target

Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/elotuzumab.html

Purity

99.9

Solubility

H2O

Smiles

[Elotuzumab]

Molecular Weight

(145.44 kDa)

References & Citations

[1]Magen H, et al. Elotuzumab: the first approved monoclonal antibody for multiple myeloma treatment. Ther Adv Hematol. 2016;7 (4) :187-195.|[2]Bezman NA, et al. PD-1 blockade enhances elotuzumab efficacy in mouse tumor models. Blood Adv. 2017 May 8;1 (12) :753-765.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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