L-Cysteinesulfinic acid (monohydrate)

L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively[1].

Product Specifications

CAS Number

[207121-48-0]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; mGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-cysteinesulfinic-acid-monohydrate.html

Concentration

10mM

Purity

99.81

Solubility

H2O : 41.67 mg/mL (ultrasonic)

Smiles

N[C@@H](CS(O)=O)C(O)=O.O

Molecular Formula

C3H9NO5S

Molecular Weight

171.17

Precautions

H315, H319, H335

References & Citations

[1]Shi Q, et al. L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists. J Pharmacol Exp Ther. 2003 Apr;305 (1) :131-42.|[2]Boss V, et al. L-cysteine sulfinic acid as an endogenous agonist of a novel metabotropic receptor coupled to stimulation of phospholipase D activity.