Asaraldehyde
Asarylaldehyde (Asaronaldehyde), a COX-2 inhibitor, significantly inhibits cyclooxygenase II (COX-2) activity with an IC50 value of 100 μg/mL[1].
Product Specifications
CAS Number
4460-86-0
Product Name Alternative
Asaronaldehyde; 2,4,5-trimethoxy-Benzaldehyde
UNSPSC
12352005
Hazard Statement
H302
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Asarylaldehyde.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=CC1=CC(OC)=C(OC)C=C1OC
Molecular Formula
C10H12O4
Molecular Weight
196.20
Precautions
H302
References & Citations
[1]Wu MR, et al. 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes. J Agric Food Chem. 2012 Jul 25;60 (29) :7262-9.|[2]Chen CC, et al. Production of a COX-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata. Lett Appl Microbiol. 2007 Apr;44 (4) :387-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2
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