Asaraldehyde

Asarylaldehyde (Asaronaldehyde), a COX-2 inhibitor, significantly inhibits cyclooxygenase II (COX-2) activity with an IC50 value of 100 μg/mL[1].

Product Specifications

CAS Number

[4460-86-0]

Product Name Alternative

Asaronaldehyde; 2,4,5-trimethoxy-Benzaldehyde

UNSPSC

12352005

Hazard Statement

H302

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Asarylaldehyde.html

Purity

99.59

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=CC1=CC(OC)=C(OC)C=C1OC

Molecular Formula

C10H12O4

Molecular Weight

196.20

Precautions

H302

References & Citations

[1]Wu MR, et al. 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes. J Agric Food Chem. 2012 Jul 25;60 (29) :7262-9.|[2]Chen CC, et al. Production of a COX-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata. Lett Appl Microbiol. 2007 Apr;44 (4) :387-92.