Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HDAC3-IN-T247

HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells[1].

Product Specifications

CAS Number

1451042-18-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/hdac3-in-t247.html

Purity

98.91

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CN(CCC3=CSC=C3)N=N2)C=C1)NC4=C(N)C=CC=C4

Molecular Formula

C21H19N5OS

Molecular Weight

389.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Suzuki T, et al. Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly. PLoS One. 2013 Jul 16;8 (7) :e68669.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC3; HDAC4; HDAC6; HDAC8

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Fhit activation kit by CRISPRa
GA201417 1 Kit

Mouse Fhit activation kit by CRISPRa

Sign In for Pricing
View Details
Pyridine-d5
TRC-P991237-1G 1 g

Pyridine-d5

Sign In for Pricing
View Details
CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: SPM489]
AM50146PU-T 20 µg

CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: SPM489]

Sign In for Pricing
View Details
Ritodrine Hydrochloride
TRC-R533700-250MG 250 mg

Ritodrine Hydrochloride

Sign In for Pricing
View Details
Frozen Tissue Sections, Lung
CS508084 5x 5 µm

Frozen Tissue Sections, Lung

Sign In for Pricing
View Details
POLR3D (NM_001722) Human Over-expression Lysate
LY400649 100 µg

POLR3D (NM_001722) Human Over-expression Lysate

Sign In for Pricing
View Details