MMP-9, Human (HEK293, C-His)

MMP-9 Protein, a matrix metalloproteinase, plays a crucial role in localized extracellular matrix breakdown, facilitating leukocyte migration. Its potential involvement in bone osteoclastic resorption is suggested. MMP-9 cleaves KiSS1 and NINJ1, generating their secreted forms. It degrades type IV and type V collagen, producing distinct fragments, and fibronectin, while laminin and Pz-peptide remain unaffected. MMP-9 Protein, Human (HEK293, C-His) is the recombinant human-derived MMP-9 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MMP-9 Protein, Human (HEK293, C-His) is 689 a.a., with molecular weight of ~82.5 kDa.

AAPRQRQSTL VLFPGDLRTN LTDRQLAEEY LYRYGYTRVA EMRGESKSLG PALLLLQKQL SLPETGELDS ATLKAMRTPR CGVPDLGRFQ TFEGDLKWHH HNITYWIQNY SEDLPRAVID DAFARAFALW SAVTPLTFTR VYSRDADIVI QFGVAEHGDG YPFDGKDGLL AHAFPPGPGI QGDAHFDDDE LWSLGKGVVV PTRFGNADGA ACHFPFIFEG RSYSACTTDG RSDGLPWCST TANYDTDDRF GFCPSERLYT QDGNADGKPC QFPFIFQGQS YSACTTDGRS DGYRWCATTA NYDRDKLFGF CPTRADSTVM GGNSAGELCV FPFTFLGKEY STCTSEGRGD GRLWCATTSN FDSDKKWGFC PDQGYSLFLV AAHEFGHALG LDHSSVPEAL MYPMYRFTEG PPLHKDDVNG IRHLYGPRPE PEPRPPTTTT PQPTAPPTVC PTGPPTVHPS ERPTAGPTGP PSAGPTGPPT AGPSTATTVP LSPVDDACNV NIFDAIAEIG NQLYLFKDGK YWRFSEGRGS RPQGPFLIAD KWPALPRKLD SVFEERLSKK LFFFSGRQVW VYTGASVLGP RRLDKLGLGA DVAQVTGALR SGRGKMLLFS GRRLWRFDVK AQMVDPRSAS EVDRMFPGVP LDTHDVFQYR EKAYFCQDRF YWRVSSRSEL NQVDQVGYVT YDILQCPED