MC-AAA-NHCH2OCH2COOH
MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC) [1].
Product Specifications
CAS Number
[2414594-28-6]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-aaa-nhch2och2cooh.html
Purity
98.56
Solubility
10 mM in DMSO
Smiles
OC(COCNC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C)=O)C)=O)C)=O)=O
Molecular Formula
C22H33N5O9
Molecular Weight
511.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10 (10) :1386-1392.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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