What is the catalog number for Go6976?

The catalog number for Go6976 is HY-10183.

What sizes are available for Go6976?

Go6976 is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Go6976 come in?

Go6976 is available in 7 different pack sizes.

Go6976 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Go6976?

Go6976 is manufactured by QuantiMol.

What is the estimated delivery time for Go6976?

Estimated delivery time for Go6976 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Go6976?

The safety data sheet for Go6976 is available here: http://file.medchemexpress.com/batch_PDF/HY-10183/Go6976-SDS-MedChemExpress.pdf.

Go6976

Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM.

Product Specifications

CAS Number

136194-77-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Influenza Virus; PKC

Type

Reference compound

Related Pathways

Anti-infection; Epigenetics; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Go_6976.html

Purity

99.57

Solubility

DMSO : 65 mg/mL (ultrasonic)

Smiles

N#CCCN(C1=C2C(CNC3=O)=C3C4=C1N(C)C5=C4C=CC=C5)C6=C2C=CC=C6

Molecular Formula

C24H18N4O

Molecular Weight

378.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Qatsha KA, et al. Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A. 1993 May 15;90 (10) :4674-8.|[2]Hayamitsu Adachi, et al. Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. The Journal of Antibiotics volume 71, pages 60–71 (2018) .|[3]Mahmoudian S, et al. Influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C. J Gen Virol. 2009;90 (Pt 6) :1392-1397.