What is the catalog number for XO44?

The catalog number for XO44 is HY-122609.

What sizes are available for XO44?

XO44 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does XO44 come in?

XO44 is available in 6 different pack sizes.

XO44 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures XO44?

XO44 is manufactured by QuantiMol.

What is the estimated delivery time for XO44?

Estimated delivery time for XO44 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for XO44?

The safety data sheet for XO44 is available here: http://file.medchemexpress.com/batch_PDF/HY-122609/XO44-SDS-MedChemExpress.pdf.

XO44

XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK2 and CDK1. XO44 also labels CDK4 proteins in cells[1][2].

Product Specifications

CAS Number

2088112-70-1

Product Name Alternative

PF-6808472

UNSPSC

12352005

Hazard Statement

H314

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/xo44.html

Purity

99.38

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C(CN2CCN(C3=NC(C(NCC#C)=O)=CC(NC4=NNC(C5CC5)=C4)=N3)CC2)C=C1)(F)=O

Molecular Formula

C25H27FN8O3S

Molecular Weight

538.60

Precautions

H314

References & Citations

[1]Kevin D Freeman-Cook, et al. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J Med Chem. 2021 Jul 8;64 (13) :9056-9077.|[2]Guiley KZ, et al. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science. 2019 Dec 13;366 (6471) :eaaw2106.