Arteannuin B

Arteannuin B, No. 2000 can be jointly submitted with the blue material. Arteannuin B had anti-SARS-CoV-2 activity, EC50=10.28 μM[1][2][3].

Product Specifications

CAS Number

[50906-56-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Ferroptosis; SARS-CoV

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/arteannuin-b.html

Purity

99.89

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@]1(CC[C@]2([H])[C@@]3(OC4=O)[C@](CC[C@H]2C)([H])C4=C)[C@H]3O1

Molecular Formula

C15H20O3

Molecular Weight

248.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Ruiyuan Cao, et al. Anti-SARS-CoV-2 Potential of Artemisinins In Vitro. RETURN TO JUST ACCEPTED MANUSCRIPTS.|[2]Nair MS, et al. Bioconversion of arteannuin B to artemisinin. J Nat Prod. 1993 Sep;56 (9) :1559-66.|[3]Varela K, et al. Inhibition of Cysteine Proteases via Thiol-Michael Addition Explains the Anti-SARS-CoV-2 and Bioactive Properties of Arteannuin B. J Nat Prod. 2023 Jul 28;86 (7) :1654-1666.|[4]Huang W, et al. Arteannuin B Enhances the Effectiveness of Cisplatin in Non-Small Cell Lung Cancer by Regulating Connexin 43 and MAPK Pathway. Am J Chin Med. 2022;50 (7) :1963-1992.