Cl-C6-PEG4-O-CH2COOH

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) [1].

Product Specifications

CAS Number

[1799506-30-1]

Product Name Alternative

PROTAC Linker 4

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PROTAC_Linker_4.html

Purity

99.46

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

ClCCCCCCOCCOCCOCCOCCOCC(O)=O

Molecular Formula

C16H31ClO7

Molecular Weight

370.87

Precautions

H302, H315, H319, H335

References & Citations

[1]Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10 (8) :1831-7.