Cl-C6-PEG4-O-CH2COOH
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) [1].
Product Specifications
CAS Number
[1799506-30-1]
Product Name Alternative
PROTAC Linker 4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PROTAC_Linker_4.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)
Smiles
ClCCCCCCOCCOCCOCCOCCOCC(O)=O
Molecular Formula
C16H31ClO7
Molecular Weight
370.87
Precautions
H302, H315, H319, H335
References & Citations
[1]Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10 (8) :1831-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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