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XIE62-1004-A

Product Specifications

UNSPSC Description

XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy[1].

Target Antigen

Atg8/LC3; Autophagy; p62

Type

Reference compound

Related Pathways

Autophagy

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xie62-1004-a.html

Purity

99.89

Solubility

DMSO : 125 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

OCCNCC1=CC=C(C(OCC2=CC=CC=C2)=C1)OCC3=CC=CC=C3.Cl

Molecular Weight

399.91

References & Citations

[1]Horos R, et al. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 2019;176(5):1054-1067.e12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W688687/XIE62-1004-A-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W688687/XIE62-1004-A-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2421146-32-7

Available Sizes

Curated Selection

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