XIE62-1004-A
XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy[1].
Product Specifications
CAS Number
[2421146-32-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Atg8/LC3; Autophagy; p62
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/xie62-1004-a.html
Purity
99.89
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OCCNCC1=CC=C(C(OCC2=CC=CC=C2)=C1)OCC3=CC=CC=C3.Cl
Molecular Formula
C23H26ClNO3
Molecular Weight
399.91
Precautions
H302, H315, H319
References & Citations
[1]Horos R, et al. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 2019;176 (5) :1054-1067.e12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
SRGN (Serglycin, Hematopoietic Proteoglycan Core Protein, Platelet Proteoglycan Core Protein, P.PG, Secretory Granule Proteoglycan Core Protein, PRG, PRG1, FLJ12930, MGC9289) (MaxLight 550)
Mouse Monoclonal PDX-1/IPF1 Antibody (267712) [DyLight 650]
