XIE62-1004-A

XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy[1].

Product Specifications

CAS Number

[2421146-32-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Atg8/LC3; Autophagy; p62

Type

Reference compound

Related Pathways

Autophagy

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xie62-1004-a.html

Purity

99.89

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OCCNCC1=CC=C(C(OCC2=CC=CC=C2)=C1)OCC3=CC=CC=C3.Cl

Molecular Formula

C23H26ClNO3

Molecular Weight

399.91

Precautions

H302, H315, H319

References & Citations

[1]Horos R, et al. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 2019;176 (5) :1054-1067.e12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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