GJ071 (oxalate)
GJ071 oxalate induces ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons[1].
Product Specifications
CAS Number
[1216676-34-4]
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gj071-oxalate.html
Purity
99.74
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
S=C(N1CCN(CC2=CC=C(OCO3)C3=C2)CC1)NCCCOCC.O=C(O)C(O)=O
Molecular Formula
C20H29N3O7S
Molecular Weight
455.53
References & Citations
[1]Du L, et al. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep;21 (9) :1653-60.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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