Pseudohypericin
Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity[1][2].
Product Specifications
CAS Number
55954-61-5
UNSPSC
12352005
Hazard Statement
H302
Target
HIV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pseudohypericin.html
Purity
99.23
Solubility
10 mM in DMSO
Smiles
O=C1C2=C3C4=C5C1=C(O)C=C(CO)C5=C6C(C)=CC(O)=C7C6=C4C8=C(C(O)=CC(O)=C8C3=C(O)C=C2O)C7=O
Molecular Formula
C30H16O9
Molecular Weight
520.44
Precautions
H302
References & Citations
[1]Lavie G, et al. Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin. Proc Natl Acad Sci U S A. 1989 Aug;86 (15) :5963-7.|[2]Zheng X, et al. Apoptosis of THP-1 Macrophages Induced by Pseudohypericin-Mediated Sonodynamic Therapy Through the Mitochondria-Caspase Pathway. Cell Physiol Biochem. 2016;38 (2) :545-57.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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