TG 100713
TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1].
Product Specifications
CAS Number
925705-73-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tg-100713.html
Purity
99.49
Solubility
DMSO : 6.41 mg/mL (ultrasonic)
Smiles
OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1
Molecular Formula
C12H10N6O
Molecular Weight
254.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Doukas J, et, al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103 (52) :19866-71.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
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