P-selectin antagonist 1
Product Specifications
UNSPSC Description
P-selectin antagonist 1 (Compound 11b) is an antagonist for pan-selectin (IC50 is 82 μM) and E-selectin (KD is 0.91 μM)[1].
Target Antigen
P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/p-selectin-antagonist-1.html
Smiles
O=C([C@@H]1C[C@@H]([C@H]([C@@H](C1)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@@H](CC3CCCCC3)C(O[Na])=O)OC(C4=CC=CC=C4)=O)O[C@@H]5O[C@H]([C@H]([C@H]([C@@H]5O)O)O)C)CC)NCCCC6=CN(N=N6)CCCC(NC7=C8C(C=C(C=C8S(=O)(O[Na])=O)S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C7)=O
Molecular Weight
1402.34
References & Citations
[1]Wagner B, et al., Analogues of the pan-selectin antagonist rivipansel (GMI-1070). Eur J Med Chem. 2024 Jun 5;272:116455.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161646/P-selectin-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161646/
Clinical Information
No Development Reported
CAS Number
2099111-75-6
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