P-selectin antagonist 1
Product Specifications
CAS Number
[2099111-75-6]
UNSPSC Description
P-selectin antagonist 1 (Compound 11b) is an antagonist for pan-selectin (IC50 is 82 μM) and E-selectin (KD is 0.91 μM)[1].
Target Antigen
P-selectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/p-selectin-antagonist-1.html
Smiles
O=C([C@@H]1C[C@@H]([C@H]([C@@H](C1)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@@H](CC3CCCCC3)C(O[Na])=O)OC(C4=CC=CC=C4)=O)O[C@@H]5O[C@H]([C@H]([C@H]([C@@H]5O)O)O)C)CC)NCCCC6=CN(N=N6)CCCC(NC7=C8C(C=C(C=C8S(=O)(O[Na])=O)S(=O)(O[Na])=O)=CC(S(=O)(O[Na])=O)=C7)=O
Molecular Weight
1402.34
References & Citations
[1]Wagner B, et al., Analogues of the pan-selectin antagonist rivipansel (GMI-1070). Eur J Med Chem. 2024 Jun 5;272:116455.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-77983 10 Slides
Stomach Matched Primary Tumor & Metastatic Tumor Slides (Tumor)
Sign In for Pricing
View Details 
K7040207 1.0 µg DNA
Gne sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details 
243509 100 µg
ARRB2 (Arrestin, beta 2, ARB2, ARR2, BARR2, DKFZp686L0365)
Sign In for Pricing
View Details NBP2-98103AF532 0.1 mL
Rabbit Polyclonal Ephrin-A2 Antibody [Alexa Fluor 532]
Sign In for Pricing
View Details GTR15169367 1 Vial
Lentiviral mouse Shld2 shRNA (UAS) - Lentiviral mouse Shld2 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details