Alexidine (dihydrochloride)

Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens[1].

Product Specifications

CAS Number

[1715-30-6]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/alexidine-dihydrochloride.html

Purity

99.68

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

N=C(NCC(CC)CCCC)NC(NCCCCCCNC(NC(NCC(CC)CCCC)=N)=N)=N.[H]Cl.[H]Cl

Molecular Formula

C26H58Cl2N10

Molecular Weight

581.71

Precautions

H302, H315, H319, H335

References & Citations

[1]Mamouei Z, et al. Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens. mSphere. 2018 Oct 31;3 (5) . pii: e00539-18.