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[Leu31,Pro34]-Neuropeptide Y (human,rat)

Product Specifications

UNSPSC Description

[Leu31,Pro34]-Neuropeptide Y(human,rat) is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) can increase blood pressure in anesthetized rats and increases food intake[1][2].

Target Antigen

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/leu31-pro34-neuropeptide-y-human-rat.html

Solubility

H2O

Smiles

N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N4CCC[C@H]4C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5CCC[C@H]5C(N[C@H](C(N[C@H](C(N)=O)CC6=CC=C(C=C6)O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)[C@H](O)C)=O)CC(C)C)=O)CC(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC7=CC=C(C=C7)O)=O)CC8=CNC=N8)=O)CCCNC(N)=N)=O)CC(C)C)=O)C)=O)CO)=O)CC9=CC=C(C=C9)O)=O)CC%10=CC=C(C=C%10)O)=O)CCCNC(N)=N)=O)C)=O)CCSC)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)C)=O)CC(O)=O)=O)CCC(O)=O)=O)=O)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CCCCN)=O)CO)=O)=O)CC%11=CC=C(C=C%11)O

Molecular Weight

4240.73

References & Citations

[1]J Fuhlendorff, et al. [Leu31, Pro34]neuropeptide Y: a specific Y<sub>1</sub> receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6.|[2]K McCrea, et al. 2-36[K4,RYYSA(19-23)]PP a novel Y<sub>5</sub>-receptor preferring ligand with strong stimulatory effect on food intake. Regul Pept. 2000 Feb 8;87(1-3):47-58.|[3]A Kask, et al. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y<sub>1</sub>-selective antagonist BIBP3226. Br J Pharmacol. 1998 Aug;124(7):1507-15.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P1323/Leu31-Pro34-Neuropeptide-Y-human-rat-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P1323/

Clinical Information

No Development Reported

CAS Number

132699-73-1

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