Endothelin 1 (swine, human)

Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB[1].

Product Specifications

CAS Number

[117399-94-7]

UNSPSC

12352209

Hazard Statement

H301, H311, H331

Target

Endothelin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Endothelin_1_swine,_human.html

Purity

99.12

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]2([H])NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@](CSSC2)([H])NC([C@@H](NC([C@H](CSSC1)N)=O)CO)=O)=O)CO)=O)CO)=O)CC(C)C)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)=O)C(C)C)=O)CC3=CC=C(C=C3)O)=O)CC4=CC=CC=C4)=O)N[C@@H](CC5=CN=CN5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O

Molecular Formula

C109H159N25O32S5

Molecular Weight

2491.90

Precautions

H301, H311, H331

References & Citations

[1]Kowalczyk A, et al. The role of endothelin-1 and endothelin receptor antagonists in inflammatory response andsepsis. Arch Immunol Ther Exp (Warsz) . 2015 Feb;63 (1) :41-52.