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AF/LE Purified Anti-Human CD154 Antibody[24-31]

Product Specifications

Background

CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Abbreviation

CD154

Gene ID

959

UniProt

P29965

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD154 protein

Target

IMD; HIGM; T-Cell Antigen Gp; Tumor Necrosis Factor Ligand Superfamily Member; TNFSF; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L; CD40LG; CD40 Ligand; CD40-L; T-Cell Antigen Gp39; TNF-Related Activation Protein; Tumor Necrosis Factor Ligand Superfamily Member 5; T-BAM; gp39; TRAP; TNFSF5; TNFSF5; CD40LG

Clonality

Monoclonal

Clone

24-31

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Cardiovascular

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG1, κ

Available Sizes

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