3-epi-Vitamin D3
3-epi-Vitamin D3 (Epicholecalciferol) (Compound 4), a Vitamin D3 analogue, is a Hedgehog pathway inhibitor with an IC50 of 39.2 μM measured in U87MG cells[1].
Product Specifications
CAS Number
[57651-82-8]
Product Name Alternative
Epicholecalciferol
UNSPSC
12352211
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-epi-vitamin-d3.html
Purity
94.48
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])/C(CCC1)=C/C=C3C(CC[C@H](C\3)O)=C
Molecular Formula
C27H44O
Molecular Weight
384.64
References & Citations
[1]Banerjee U, et al. Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors. Bioorg Med Chem Lett. 2012 Feb 1;22 (3) :1330-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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