4-Methyl-4- (methyldisulfanyl) pentanoic acid
4-Methyl-4- (methyldisulfanyl) pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[796073-55-7]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-methyl-4-methyldisulfanyl-pentanoic-acid.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(SSC)(C)CCC(O)=O
Molecular Formula
C7H14O2S2
Molecular Weight
194.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Available Sizes
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