6-O-Methylcatalpol
6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC50: 32.5 and 8.3 μg/mL) [1][2].
Product Specifications
CAS Number
[1617-84-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/6-o-methylcatalpol.html
Solubility
10 mM in DMSO
Smiles
OC[C@]1([C@@]2([H])O1)[C@]([C@@H]3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)([H])[C@](C=CO3)([H])[C@@H]2OC
Molecular Formula
C16H24O10
Molecular Weight
376.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Niu ZR, et al. A new iridoid glycoside from Scrophularia ningpoensis. Nat Prod Res. 2009;23 (13) :1181-8.|[2]Tasdemir D, et al. Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots. Phytochemistry. 2005 Feb;66 (3) :355-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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