Recombinant MAP2K2 Protein

<strong>Recombinant MAP2K2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017652_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 45.7 kDa_x000D_ <strong>Supplied as:</strong> SOLUTION_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAPKK2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bomar L, Senithilnathan A, Ahn C. Systemic Therapies for Advanced Melanoma Dermatol Clin. 2019 Oct;37(4):409-423._x000D_ 2: Yamamoto T, Tsigelny IF, Götz AW, Howell SB. Cisplatin inhibits MEK1/2 Oncotarget. 2015 Sep 15;6(27):23510-22._x000D_ 3: Jiménez-Pérez L, Cidad P, Álvarez-Miguel I, Santos-Hipólito A, Torres-Merino R, Alonso E, de la Fuente MÁ, López-López JR, Pérez-García MT. Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation J Biol Chem. 2016 Feb 12;291(7):3569-80._x000D_ 4: Nadeau V, Charron J. Essential role of the ERK/MAPK pathway in blood-placental barrier formation Development. 2014 Jul;141(14):2825-37._x000D_ 5: Zheng CF, Guan KL. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2 J Biol Chem. 1993 May 25;268(15):11435-9._x000D_ 6: Kanki H, Sasaki T, Matsumura S, Yokawa S, Yukami T, Shimamura M, Sakaguchi M, Furuno T, Suzuki T, Mochizuki H. β-arrestin-2 in PAR-1-biased signaling has a crucial role in endothelial function via PDGF-β in stroke Cell Death Dis. 2019 Feb 4;10(2):100._x000D_ 7: Yang KY, Liu Y, Zhang S. Activation of a mitogen-activated protein kinase pathway is involved in disease resistance in tobacco Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):741-6._x000D_ 8: Sato S, Fujita N, Tsuruo T. Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway J Biol Chem. 2004 Aug 6;279(32):33759-67._x000D_ 9: Ehses JA, Pelech SL, Pederson RA, McIntosh CH. Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway J Biol Chem. 2002 Oct 4;277(40):37088-97._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8621389">10: Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase J Biol Chem. 1996 Mar 8;271(10):5361-8. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant MAP2K2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>