Glufosinate

Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin) . Glufosinate exerts neurotoxic activity[1][2].

Product Specifications

CAS Number

[51276-47-2]

UNSPSC

12352211

Hazard Statement

H302-H312-H332-H361-H370-H373-H400-H410

Target

Herbicide

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/glufosinate.html

Purity

90.00

Solubility

10 mM in DMSO

Smiles

CP(O)(CCC(N)C(O)=O)=O

Molecular Formula

C5H12NO4P

Molecular Weight

181.13

Precautions

P260-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P363-P391-P405-P501

References & Citations

[1]Áy Z, et al. The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. ScientificWorldJournal. 2012;2012:657945.|[2]Feat-Vetel J, et al. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology. 2018 Dec;69:152-163.|[3]Ebert E, et al. Summary of safety evaluation toxicity studies of glufosinate ammonium. Food Chem Toxicol. 1990 May;28 (5) :339-49.