Mad1 (6-21)

Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1].

Product Specifications

CAS Number

[880150-82-3]

UNSPSC

12352209

Target

HDAC

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mad1-6-21.html

Purity

98.02

Solubility

H2O

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(N)=O)NC([C@H](CCSC)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O

Molecular Formula

C84H140N24O26S2

Molecular Weight

1966.29

References & Citations

[1]K Brubaker, et al. Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex. Cell. 2000 Nov 10;103 (4) :655-65.