Adenosylcobalamin

Adenosylcobalamin (Coenzyme B12; Cobamamide; AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]

Product Specifications

CAS Number

[13870-90-1]

Product Name Alternative

Coenzyme B12; Cobamamide; AdoCbl

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adenosylcobalamin.html

Purity

99.15

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O)[CH2-][Co+3]456([N]7=CN([C@@H](O[C@H](CO)[C@H]8OP9([O-])=O)[C@]8([H])O)C%10=CC(C)=C(C)C=C7%10)[N]%11=C%12[C@@H](CCC(N)=O)[C@@](CC(N)=O)(C)[C@]%11(C)[C@]([C@H](CC(N)=O)[C@]%13(CCC(NC[C@@H](C)O9)=O)C)([H])[N-]4C%13=C(C)C([C@@H](CCC(N)=O)C%14(C)C)=[N]5C%14=CC%15=[N]6C([C@](CC(N)=O)(C)[C@@H]%15CCC(N)=O)=C%12C

Molecular Formula

C72H100CoN18O17P

Molecular Weight

1579.58

Precautions

H315, H319, H320

References & Citations

[1]Kumudha A, et al. Characterization of vitamin B12 in Dunaliella salina. J Food Sci Technol. 2016 Jan;53 (1) :888-94.|[2]Marsh EN, et al. Adenosylcobalamin enzymes: Theory and experiment begin to converge. Biochim Biophys Acta. 2012 Nov;1824 (11) :1154-64.