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Tauro-obeticholic acid-d5 (sodium)

Selected Variant

HY-135399S-01

Size: 1 mg

Tauro-obeticholic acid-d5 sodium is deuterium labeled Tauro-obeticholic acid sodium. Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1][2].

Product Specifications

UNSPSC

12352211

Target

Drug Metabolite; FXR; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@]3([H])[C@]([C@@H]([C@@H]([C@]1([H])C[C@@H](CC2)O)C([2H])([2H])C([2H])([2H])[2H])O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCCS(=O)(O[Na])=O)=O)C

Molecular Formula

C28H43D5NNaO6S

Molecular Weight

554.77

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Xiaojiao Li, et al. Comparison of the Pharmacokinetics of Generic Versus Branded Obeticholic Acid in a Chinese Population: Effects of Food and Sex. Clin Pharmacol Drug Dev. 2021 Jul;10 (7) :797-806.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Price

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