Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ralmitaront

Ralmitaront (RO6889450) is an orally active agonist of trace amine-associated receptor 1 (TAAR1) with a EC50 value of 110.4 nM. Ralmitaront has antipsychotic, cognitively improvement, and antidepressant activity in rodents. Ralmitaront can be used as a neurosuppressant in the study of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder[1][2][3][4].

Product Specifications

CAS Number

[2133417-13-5]

Product Name Alternative

RO6889450

UNSPSC

12352005

Target

5-HT Receptor; Dopamine Receptor; Trace Amine-associated Receptor (TAAR)

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ralmitaront.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=NNC(CC)=C1C)NC2=CC=C([C@H]3CNCCO3)C=C2

Molecular Formula

C17H22N4O2

Molecular Weight

314.38

References & Citations

[1]Linda S Brady, et al. Redirecting the revolution: new developments in drug development for psychiatry. Expert Opin Drug Discov. 2019 Dec;14 (12) :1213-1219.|[2]Halff EF, et al. Trace amine-associated receptor 1 (TAAR1) agonism as a new treatment strategy for schizophrenia and related disorders. Trends Neurosci. 2023 Jan;46 (1) :60-74. |[3]Ågren R, et al. In Vitro Comparison of Ulotaront (SEP-363856) and Ralmitaront (RO6889450) : Two TAAR1 Agonist Candidate Antipsychotics. Int J Neuropsychopharmacol. 2023 Sep 25;26 (9) :599-606. |[4]Yu J, et al. Elucidating the molecular pharmacology of trace amine-associated receptor 1 to advance antipsychotic drug discovery. Clin Transl Med. 2024 Feb;14 (2) :e1576.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109157/Ralmitaront-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109157/Ralmitaront-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RPS15AP39 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
42138111 3 x 1.0 µg

RPS15AP39 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

Ask
View Details
ELISA Kit For Tumor necrosis factor receptor superfamily member 18
E9333m 96 Tests

ELISA Kit For Tumor necrosis factor receptor superfamily member 18

Ask
View Details
Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)
MBS1016730-01 0.02 mg (E-Coli)

Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)

Ask
View Details
Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)
MBS1016730-02 0.1 mg (E-Coli)

Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)

Ask
View Details
Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)
MBS1016730-03 0.02 mg (Yeast)

Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)

Ask
View Details
Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)
MBS1016730-04 0.1 mg (Yeast)

Recombinant Anaerocellum thermophilum Ribosome maturation factor RimP (rimP)

Ask
View Details