Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PF-05381941

PF-05381941 is a potent dual inhibitor of TAK1/p38α, with IC50s of 156 and186 nM, respectively[1].

Product Specifications

CAS Number

[1474022-02-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

MAP3K; p38 MAPK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pf-05381941.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(OC2=CC=NC=C2)C(C)=C1)NC3=CC(C(C)(C)C)=NN3C4=CC=CC(C#N)=C4

Molecular Formula

C27H26N6O2

Molecular Weight

466.53

Precautions

H302, H315, H319

References & Citations

[1]Kilty I, et al. TAK1 inhibition in the DFG-out conformation. Chem Biol Drug Des. 2013;82 (5) :500-505.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P38α

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit anti-GCFC1 Antibody, Affinity Purified
MBS3903461-01 0.01 mg

Rabbit anti-GCFC1 Antibody, Affinity Purified

Sign In for Pricing
View Details
Rabbit anti-GCFC1 Antibody, Affinity Purified
MBS3903461-02 0.1 mg

Rabbit anti-GCFC1 Antibody, Affinity Purified

Sign In for Pricing
View Details
Rabbit anti-GCFC1 Antibody, Affinity Purified
MBS3903461-03 5x 0.01 mg

Rabbit anti-GCFC1 Antibody, Affinity Purified

Sign In for Pricing
View Details
Rabbit anti-GCFC1 Antibody, Affinity Purified
MBS3903461-04 5x 0.1 mg

Rabbit anti-GCFC1 Antibody, Affinity Purified

Sign In for Pricing
View Details
Human Complement C1q-like protein 4, C1QL4 ELISA KIT
E5094Hu-01 48 Well

Human Complement C1q-like protein 4, C1QL4 ELISA KIT

Sign In for Pricing
View Details
Human Complement C1q-like protein 4, C1QL4 ELISA KIT
E5094Hu-02 96 Well

Human Complement C1q-like protein 4, C1QL4 ELISA KIT

Sign In for Pricing
View Details