MAO-B-IN-30
Product Specifications
UNSPSC Description
MAO-B-IN-30 (compound IS7) is a potent, selective and cross the blood-brain barrier MAO-B inhibitor with IC50 values of 19.176, 0.082 µM for MAO-A and MAO-B, respectively. MAO-B-IN-30 shows antiproliferative activity and non-cytotoxic. MAO-B-IN-30 reduces TNF-alpha, IL-6, NF-kB levels. MAO-B-IN-30 has the potential for the research of Parkinson's disease[1].
Target Antigen
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-30.html
Solubility
DMSO : 4.17 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(/C1=N\NC(C2=CC=C(Br)C=C2)=O)NC3=C1C=CC=C3
Molecular Weight
344.16
References & Citations
[1]Kumar S, Oh JM, Prabhakaran P, Awasti A, Kim H, Mathew B. Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect. Sci Rep. 2024 Jan 13;14(1):1264.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161240/MAO-B-IN-30-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161240/MAO-B-IN-30-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
82973-15-7
Available Sizes
Curated Selection
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