MAO-B-IN-30
MAO-B-IN-30 (compound IS7) is a potent, selective and cross the blood-brain barrier MAO-B inhibitor with IC50 values of 19.176, 0.082 µM for MAO-A and MAO-B, respectively. MAO-B-IN-30 shows antiproliferative activity and non-cytotoxic. MAO-B-IN-30 reduces TNF-alpha, IL-6, NF-kB levels. MAO-B-IN-30 has the potential for the research of Parkinson's disease[1].
Product Specifications
CAS Number
[82973-15-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-30.html
Purity
98.53
Solubility
DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(/C1=N\NC(C2=CC=C(Br)C=C2)=O)NC3=C1C=CC=C3
Molecular Formula
C15H10BrN3O2
Molecular Weight
344.16
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Available Sizes
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