(R) -Filanesib
(R) -Filanesib ((R) -ARRY-520) is the R-enantiomer of Filanesib (HY-15187) . Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor with an IC50 of 6 nM.
Product Specifications
CAS Number
[885060-08-2]
Product Name Alternative
(R) -ARRY-520
UNSPSC
12352005
Hazard Statement
H302-H335
Target
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arry-520-r-enantiomer.html
Purity
98.80
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1[C@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C
Molecular Formula
C20H22F2N4O2S
Molecular Weight
420.48
Precautions
P261-P264-P270-P271-P304+P340-P330-P403+P233-P405-P501
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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