FATP1-IN-1

FATP1-IN-1 (compound 5k) is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively[1].

Product Specifications

CAS Number

[1431945-95-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

FATP

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fatp1-in-1.html

Concentration

10mM

Purity

99.55

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC(CCCC2)=C2S1)CN3CCN(C4=NC=C(F)C=C4)CC3

Molecular Formula

C18H22FN5OS

Molecular Weight

375.46

Precautions

H315, H319, H320

References & Citations

[1]Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23 (9) :2560-2565.