FATP1-IN-1
FATP1-IN-1 (compound 5k) is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively[1].
Product Specifications
CAS Number
[1431945-95-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
FATP
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fatp1-in-1.html
Concentration
10mM
Purity
99.55
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC(CCCC2)=C2S1)CN3CCN(C4=NC=C(F)C=C4)CC3
Molecular Formula
C18H22FN5OS
Molecular Weight
375.46
Precautions
H315, H319, H320
References & Citations
[1]Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23 (9) :2560-2565.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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