BC-1215
Product Specifications
Product Name Alternative
TPEDA
UNSPSC Description
BC-1215 is a F-box protein 3 (Fbxo3) inhibitor. BC-1215 works by antagonizing of Fbxo3 on TRAF cytokine signaling and exhibits a low IC50 in vitro. BC-1215 can be used for the research of inflammation[1].
Target Antigen
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bc-1215.html
Purity
99.93
Solubility
DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
C1(CNCCNCC2=CC=C(C3=NC=CC=C3)C=C2)=CC=C(C4=NC=CC=C4)C=C1
Molecular Weight
394.51
References & Citations
[1]Chen BB, et al. A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulateinflammation. Nat Immunol. 2013 May;14(5):470-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117937/BC-1215-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117937/BC-1215-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1507370-20-8
Available Sizes
Curated Selection
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