FmocNH-PEG2-CH2CONH-PEG2-CH2COOH
FmocNH-PEG2-CH2CONH-PEG2-CH2COOH is an optimized, extended PEG-like linker[1].
Product Specifications
CAS Number
[560088-89-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmocnh-peg2-ch2conh-peg2-ch2cooh.html
Purity
99.75
Solubility
10 mM in DMSO
Smiles
O=C(O)COCCOCCNC(COCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O
Molecular Formula
C27H34N2O9
Molecular Weight
530.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Kedika SR, et al. Converting a weaker ATP-binding site inhibitor into a potent hetero-bivalent ligand by tethering to a unique peptide sequence derived from the same kinase. Org Biomol Chem. 2018 Sep 11;16 (35) :6443-6449.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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