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Thiocolchicoside

Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1].

Product Specifications

CAS Number

602-41-5

UNSPSC

12352005

Hazard Statement

H301-H341-H361-H372

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/thiocolchicoside.html

Purity

99.54

Solubility

DMSO : 233.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

CSC1=CC=C2C3=C(OC)C(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3CC[C@H](NC(C)=O)C2=CC1=O

Molecular Formula

C27H33NO10S

Molecular Weight

563.62

Precautions

P260-P264-P270-P280-P330-P405-P501

References & Citations

A

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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