Thiocolchicoside
Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1].
Product Specifications
CAS Number
[602-41-5]
UNSPSC
12352005
Hazard Statement
H301-H341-H361-H372
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thiocolchicoside.html
Purity
99.54
Solubility
DMSO : 233.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
CSC1=CC=C2C3=C(OC)C(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3CC[C@H](NC(C)=O)C2=CC1=O
Molecular Formula
C27H33NO10S
Molecular Weight
563.62
Precautions
P260-P264-P270-P280-P330-P405-P501
References & Citations
A
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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