Sn-Glycerol 3-phosphate

Sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP) . Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism[1][2].

Product Specifications

CAS Number

[17989-41-2]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Glycerol_3-phosphate.html

Concentration

10mM

Purity

98.0

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O[C@H](CO)COP(O)(O)=O

Molecular Formula

C3H9O6P

Molecular Weight

172.07

References & Citations

[1]Frasson D, et al. The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats. Metabolism. 2012 Oct;61 (10) :1473-85. |[2]Shen W, et al. Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell. 2006 Feb;18 (2) :422-41.