Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5)

Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) is an active compound for toxoplasmic encephalitis inhibition, as well as inhibition in protozoan and bacterial infections[1][2].

Product Specifications

CAS Number

[8064-90-2]

UNSPSC

12352005

Hazard Statement

H302, H361

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cotrimoxazole-trimethoprim-sulfamethoxazole-1-5.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(NC1=NOC(C)=C1)(C2=CC=C(C=C2)N)=O.NC3=NC=C(CC4=CC(OC)=C(C(OC)=C4)OC)C(N)=N3

Molecular Formula

C24H29N7O6S

Molecular Weight

543.60

Precautions

H302, H361

References & Citations

[1]Béraud G, et al. Cotrimoxazole for treatment of cerebral toxoplasmosis: an observational cohort study during 1994-2006. Am J Trop Med Hyg. 2009 Apr;80 (4) :583-7.|[2]Thyagarajan B, et al. Cotrimoxazole and neonatal kernicterus: a review. Drug Chem Toxicol. 2014 Apr;37 (2) :121-9.