Coenzyme Q10

Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

Product Specifications

CAS Number

[303-98-0]

Product Name Alternative

CoQ10; Ubiquinone-10; Ubidecarenone

UNSPSC

12352211

Hazard Statement

H315, H319, H320

Target

Endogenous Metabolite; Ferroptosis; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Coenzyme_Q10.html

Purity

99.69

Solubility

DMF : 20 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)C(C(OC)=C1OC)=O

Molecular Formula

C59H90O4

Molecular Weight

863.34

Precautions

H315, H319, H320

References & Citations

[1]Yang YK, et al. Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clin Chim Acta. 2015 Oct 23;450:83-9.|[2]Bhagavan HN, et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006 May;40 (5) :445-53.|[3]Matthews RT, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95 (15) :8892-7.