GGDPS-IN-1
Product Specifications
UNSPSC Description
GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC50 of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggdps-in-1.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(C(CC1=CN(N=N1)CC/C=C(CC/C=C(C)/C)\C)(N)P(O)(O)=O)O
Molecular Weight
422.35
References & Citations
[1]Gehrke NR, et al. α-Amino bisphosphonate triazoles serve as GGDPS inhibitors. Bioorg Med Chem Lett. 2024 Feb 17:129659.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163334/GGDPS-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163334/
Clinical Information
No Development Reported
Curated Selection
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