AADvac 1 (TFA)

AADvac 1 TFA is an active tau peptide vaccine for Alzheimer's disease research. AADvac 1 TFA is composed of a regulatory peptide 294KDNIKHVPGGGS305 that drives tau oligomerization conjugated to Aplysia hemocyanin (KLH) and formulated with aluminum hydroxide[1].

Product Specifications

UNSPSC

12352209

Target

Tau Protein

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aadvac-1-tfa.html

Purity

95.05

Smiles

[CKDNIKHVPGGGS,KLHconjugated(TFAsalt)]

References & Citations

[1]Kontsekova E, et al. First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model. Alzheimers Res Ther. 2014 Aug 1;6 (4) :44.