(±) 8 (9) -EpETE
Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±) 17 (18) -EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±) 8 (9) -EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.
Product Specifications
CAS Number
851378-93-3
Product Name Alternative
(±) 8,9-EEQ; (±) 8,9-epoxy Eicosatetraenoic acid
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/racemic-8-9-epete.html
Smiles
CC/C=C\C/C=C\C/C=C\CC1C(C/C=C\CCCC(O)=O)O1
Molecular Formula
C20H30O3
Molecular Weight
318.45
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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