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Q134R

Product Specifications

UNSPSC Description

Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research[1].

Target Antigen

Nuclear Factor of activated T Cells (NFAT)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/q134r.html

Smiles

OC1=C(N=CC=C2)C2=CC=C1[C@@H](C3=CC=C(C(F)(F)F)C=C3)NC4=NC=CC(C)=N4

Molecular Weight

410.39

References & Citations

[1]Pradoldej Sompol, et al. Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology. Aging Cell. 2021 Jul;20(7):e13416.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139464/Q134R-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139464/Q134R-SDS-MedChemExpress.pdf

CAS Number

2022949-46-6

Available Sizes

Curated Selection

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