Q134R
Product Specifications
UNSPSC Description
Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research[1].
Target Antigen
Nuclear Factor of activated T Cells (NFAT)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/q134r.html
Smiles
OC1=C(N=CC=C2)C2=CC=C1[C@@H](C3=CC=C(C(F)(F)F)C=C3)NC4=NC=CC(C)=N4
Molecular Weight
410.39
References & Citations
[1]Pradoldej Sompol, et al. Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology. Aging Cell. 2021 Jul;20(7):e13416.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139464/Q134R-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139464/Q134R-SDS-MedChemExpress.pdf
CAS Number
2022949-46-6
Available Sizes
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